Something to note about Thunder Strike is that it's a regular attack, unlike regular lightning - the Defect's lightning doesn't benefit from strength or enemies being vulnerable, though Thunder Strike does, so keep this in mind. If you need a big finisher card, Thunder Strike, which deals seven (nine upgraded) damage for every lightning orb channeled in the fight, or Fission+ (an unupgraded Fission is useless) which evokes all your orbs and gives you energy and draw for each orb evoked, are both great. It's easy to pick up several Ball Lightnings early, which can serve as a great offensive core, dealing a bit of damage in addition to channeling. The general idea when utilising lightning is to build up some focus to deal good passive damage, evoke as regularly as possible for even more damage, and take plenty of block to cover yourself on turns you're being attacked. Lightning is the easiest of the four orbs to channel, as there are countless cards that can do so. Consume gets rid of an orb slot, and in return gives you two focus (three when upgraded), which strengthens orbs - with an Inserter and Consume, you can effectively farm infinite focus. For example, if you get an Inserter from a boss fight, which gives you an extra orb slot every two turns, you might be more inclined to take a Consume if you see it.
You can never rely on seeing a specific relic, but if you come across a particularly useful one, you can make card choices that synergise with it. For example, if you get a Ball Lightning from the first fight you win, it's probably a good idea to take other cards that synergise with lightning. It's good to have some knowledge of basic deck types to understand what sorts of cards to take, but in general, just build a deck based on the cards you're seeing. Because of this, the best approach to deckbuilding is to work with what you're given, rather than try to force a specific kind of deck. It's easy to decide on a deck archetype you like the look of, but the reality of RNG means getting the cards you need is purely a matter of chance. As with all of Slay the Spire's characters, deckbuilding is a tricky process.
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